Lord Coe, who successfully led the UK’s bid for the 2012 Games, said that many of the 26 Olympic sports were facing a make-or-break situation.
He explained how they urgently needed the money the Olympics can generate to help secure survival.
The chairman of the British Olympic Association explained: “There is a very delicate ecosystem in here that is at play and it could fundamentally alter the nature of the delivery of many of these sports.
“Some of them are really struggling at the moment having had a year-and-a-half of very few events.
“I fear that some of them might actually disappear.”
He argued the impact of the sports disappearing would have a detrimental effect on public health and impact communities negatively.
However, public pressure is growing on the Japanese government to call off the Olympics.
A recent Japanese poll found 83 percent of respondents wanted the Olympics cancelled or postponed – an increase on the 69 percent who were against the Games in April.
Last week, the influential newspaper Asahi Shimbun also published an editorial calling on Prime Minister Yoshihide Suga to abandon the Games.